The essential dyad at the center - the title characters - interact little with the more peripheral characters, who have mainly been used in B plots. Morty is our avatar, and works in that capacity extremely well. Philosophers have long debated the moral implications of 'many universes' ( while realizing it's a bit sophomoric and nerdy ) 'Rick and Morty' picks at this as its stock in trade.
The strength of the show is just how amoral Rick may be but there is a strong attachment to the 'many universes' hypothesis within the show. The ending of 'Rick Potion #9' is just amazing. It is *dark*, but there are certainly moments that approach the limits of any sort of television style format.